(CNN) — Friends star Matthew Perry died as a result of “acute effects of ketamine” and subsequent drowning, an autopsy report shows.

The report, released Friday by the Los Angeles Medical Examiner’s Office, shows Perry’s blood tested positive for ketamine which is known to treat depression and anxiety.

“At the high levels of ketamine found in his postmortem blood specimens, the main lethal effects would be from both cardiovascular overstimulation and respiratory depression,” the report states.

Perry was found floating face down in the pool of his Malibu home in October. Authorities say no foul play was involved.

Perry was “reported to be receiving ketamine infusion therapy for depression and anxiety,” the autopsy report states.

The report further explains that ketamine has medical and surgical uses as an anesthetic and is also known as a recreational drug “mainly due to its ‘dissociative’ nature, indicating disconnection of mind and body. It can also have short-duration hallucinatory and psychedelic effects.”

Perry’s last known treatment was a week and a half prior to his death, the autopsy states, well beyond the time it would still be in his system from the treatment.

The-CNN-Wire
™ & © 2023 Cable News Network, Inc., a Warner Bros. Discovery Company. All rights reserved.