Multiple southbound lanes of the 405 Freeway were blocked off following a collision with multiple vehicles on Sunday night.

A witness told the California Highway Patrol that around 9:30 p.m. a crash on the southbound side of the freeway just north of Mulholland Drive was blocking middle lanes with one vehicle on fire.

Four vehicles were involved and four patients were evaluated, according to the Los Angeles Fire Department’s Margaret Stewart.

One man and two women were taken to a hospital, she said. A boy was evaluated but was not taken to a hospital by ambulance.

Traffic trickled through the HOV lane until the CHP reported all of the vehicles were moved to the right shoulder at 10:41 p.m.