NewsNation anchor Chris Cuomo said the Democratic Party in New York City has veered too far to the left for his centrist brother to mount a successful bid for mayor.

Cuomo, who was fired by CNN in 2021 for allegedly helping then-Gov. Andrew Cuomo with public relations and crisis management advice in the face of sexual harassment allegations, was concerned about the toll the race would take on his sibling.

“I feel like he’s done so much and there’s such a high price for getting into that game now — especially in his party — that I don’t know why he seems so motivated to serve,” the younger Cuomo, 54, said on his show Monday.

Speculation about who will run for mayor ramped up after Eric Adams was indicted by the federal government last month on charges of accepting illegal campaign contributions and bribes from foreign nationals.

Chris Cuomo said his brother was “hearing people tell him to run,” though he cautioned: “Man, there’s a lot of ifs in this.”

“How radicalized left is the party structure in that special election or primary? Who else runs?”

His comments were reported by the news site Mediaite.

Cuomo wondered whether Adams will serve out his term or resign — triggering a special election.

“I think there are a lot of pieces, but the most important piece is my brother’s conviction,” Chris Cuomo said.

“And all I know is he does not share my disrespect for the process.”

Rich Azzopardi, a spokesperson for Andrew Cuomo, told The Post: “Even you guys know Governor Cuomo has no bigger supporter than Chris.”

“This is all premature, but politics is ugly and the process can be brutal, but the governor still believes in public service, no matter the personal cost,” Azzopardi said, adding: “Chris respects that, as he said.”

Adams has pleaded not guilty. He has insisted that he has no plans to resign.

The mayor said Monday that he had accepted the resignation of his deputy mayor for public safety, Philip Banks, the latest senior official to leave as the mayor fends off an indictment and calls to step down.

Adams’ director of Asian affairs, Winnie Greco, also resigned and the city fired another former aide, Rana Abbasova, who previously served as the mayor’s liaison to the Turkish community, a spokesperson for City Hall said Monday evening.

Andrew Cuomo, who resigned the governorship in 2022 after several women came forward to accuse him of harassment, was looking to get back into politics before the Adams indictment.

He has denied the allegations of sexual harassment.

A coalition of progressive forces in local politics that includes labor, business and advocacy groups is beginning to plan a counter-effort designed at preventing a Cuomo comeback as mayor, according to Politico.

But the former governor’s spokesperson dismissed the idea that unions wouldn’t support a potential Cuomo mayoral bid.

“Whomever is desperately spinning this about organized labor, forgetting the governor’s decades-long  relationship with them and his record of delivering on issues such as a $15 minimum wage, paid family leave and once-in-a-generation infrastructure projects, doesn’t pass the smell test,” Azzopardi told The Post.